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RR-11a analog
🥰Excellent
Catalog No. T12770Cas No. 685543-66-2
Alias aza-peptide Michael acceptor, 7a
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.
RR-11a analog
🥰Excellent
Purity: 98.64%
Catalog No. T12770Alias aza-peptide Michael acceptor, 7aCas No. 685543-66-2
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 202 € | In Stock | |
| 5 mg | 432 € | In Stock | |
| 10 mg | 596 € | In Stock | |
| 25 mg | 1.102 € | In Stock | |
| 50 mg | 1.881 € | In Stock | |
| 100 mg | 2.745 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 468 € | In Stock |
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Purity:98.64%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively. |
| Targets&IC50 | AE (ixodes ricinus):4.5 nM , AE1 (Trichomonas Vaginalis):4.5 nM , AE (Schistosoma mansoni):31 nM |
| In vivo | RR-11a analog shows a t1/2 of 3-10 min[2]. |
| Alias | aza-peptide Michael acceptor, 7a |
| Molecular Weight | 491.49 |
| Formula | C22H29N5O8 |
| Cas No. | 685543-66-2 |
| Smiles | CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1 |
| Relative Density. | 1.291 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 112.5 mg/mL (228.9 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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